Exhaled Nitric Oxide and Air Pollution
Omschrijving
Airborne particles have been linked to pulmonary oxidative stress and inflammation. Because these effects may be particularly great for traffic-related particles, Adar et al. (p. 507) examined associations between particle exposures and exhaled nitric oxide (FeNO) in a study of 44 senior citizens; this involved repeated trips aboard a diesel bus. Samples of (FeNO) collected before and after the trips were regressed against microenvironmental and ambient particle concentrations using mixed models controlling for multiple variables. Fine particle exposures resulted in increased levels of (FeNO) in participants, suggesting increased airway inflammation. These associations were best assessed by microenvironmental exposure measurements during periods of high personal particle exposures.
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Categorie: ontsteking - milieu
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