Cumulative Lead Exposure and Magnetic Resonance Spectroscopy
Omschrijving
Exposure to lead has adverse effects on cognition in several different human populations, but little is known about the underlying structural and functional correlates of such exposure. Using magnetic resonance spectroscopy (MRS), Weisskopf et al. (p. 519) assessed the association between cumulative exposure to lead and levels of different brain metabolite ratios in vivo and determined that cumulative lead exposure is associated with an increase in the myoinositol-to-creatine ratio. These data suggest that glial effects may be more sensitive than neuronal effects as an indicator of cumulative exposure to lead in adults.
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Categorie: lood
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