Brain works more chaotically than previously thought
Too much glutamate is the death of cells. There is, however, also an aspect to the research team's discovery that is of considerable medical interest. It has long been known that in the event of oxygen deficiency or a severe epileptic fit, large numbers of insulating cells in the white matter are destroyed. The trigger for this damage is our old friend, the neurotransmitter glutamate. "Nobody knew until now where the glutamate actually comes from," says Dr. Dietrich. "Our results might open the door to totally new therapeutic options." After all, drugs have already been developed that prevent glutamate bubbles from discharging their load into the brain. Indeed, Bonn's neuroscientists now know precisely which receptors of the insulating cells are stimulated by the neurotransmitter - another starting point for developing new drugs.
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Categorie: hersenen - glutamaat
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