Scientists Unravel Clue in Cortisol Production

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Omschrijving
When a person’s under stress or injured, the adrenal gland releases cortisol to help restore the body’s functions to normal. But the hormone’s effects are many and varied, lowering the activity of the immune system, helping create memories with short-term exposure, while impairing learning if there’s too much for too long. Given the variety of its effects,understanding how cortisol is made is essential to producing medications that can alter its production.

Scientists at the Georgia Institute of Technology have discovered an important step in cortisol production, finding that although the output of the hormone is continuous, the molecular production is cyclic in nature – involving a rhythmic binding and unbinding of a protein essential to its production. The research, which increases understanding of how the brain and the endocrine system work together to regulate health, appears in the February issue of the journal Molecular Endocrinology.

 

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Categorie: cortisol

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