Pro-vitamin E shown to be active against breast cancer cells
Omschrijving
A precursor of vitamin E has been shown to be effective against breast cancer cell lines which over-express human epidermal growth factor receptor (HER2).
About 30% of breast cancers exhibit high levels of HER2 – a feature that appears to make the disease resistant to many common treatments including chemotherapeutic agents.
Now researchers in Griffith University’s School of Medical Science have shown that pro-vitamin E or alpha-tocopheryl succinate can reduce tumour volume in experimental animals with high levels of HER2.
Chief investigator Associate Professor Jiri Neuzil said alpha-tocopheryl succinate (alpha-TOS) had the potential to be an inexpensive, safe and selective therapy for hard-to-treat breast cancers.
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