Src inhibitors may prove beneficial in breast cancer therapy

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Omschrijving
Estrogen, which binds estrogen receptor alpha (ER-alpha), is a risk factor for breast cancer development. However, one-third of new breast cancers lack detectable ER-alpha. These ER-alpha–negative cancers are more aggressive and have a worse prognosis than do ER-alpha–positive breast cancers, and have been thought to be estrogen independent. In a new JCI study, University of Miami researchers shed further light on the mechanisms regulating ER-alpha expression levels during breast cancer.

 

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Categorie: borstkanker

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