CSHL Links Activity in Brain Synapses and Developmental Abnormalities with Schizophrenia Gene

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Omschrijving
Cold Spring Harbor Laboratory (CSHL) researchers have identified a function of neuregulin1 (NRG1), a gene previously linked to schizophrenia but whose role in the disease was unknown. “We found that when this gene or this pathway is impaired,” explained CSHL’s Bo Li, “it starts a chain reaction negatively impacting synapses in the brain which contribute to the abnormal development of brain circuits and may lead to schizophrenia.”

 

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Categorie: schizofrenie

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