Blocking formation of toxic plaques implicated in type 2 diabetes

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Omschrijving
Amid growing evidence that the same abnormal clumping of proteins in Alzheimer’s disease also contributes to type-2 diabetes, scientists in New York are reporting discovery of a potent new compound that reduces formation of those so-called amyloid plaques. Their study is scheduled for the Sept. 5 issue of the Journal of the American Chemical Society, a weekly publication.The report cites evidence correlating increases in amyloid formation in the pancreas with increases in severity and rate of progression of type-2 diabetes, which affects almost 20 million Americans and is rapidly rising worldwide. Deposits of the abnormal protein damage and destroy insulin-producing “islet” cells in the pancreas. Researchers have been seeking potential new medicines that block formation of an abnormal, misfolded protein called islet amyloid polypeptide (IAPP), which may play a key role in the cell destruction.

 

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Categorie: diabetes - alzheimer

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