Rheumatoid arthritis as a modifier of periodontitis

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Omschrijving
Periodontitis is a chronic tissue-destructive condition in which the tooth-supporting collagen fibers of ligament and bone are broken down mainly by the host’s overreactive immune inflammatory response. The relation between periodontitis and other chronic inflammatory destructive diseases, such as rheumatoid arthritis (RA), has been dealt with in some studies because, in spite of their different etiologies, similar mechanisms of tissue destruction have been described in these conditions. The findings concerning the periodontal conditions of adults with RA are disputed. Some studies have shown no association between the two conditions while others have supported a worse periodontal status in these patients. Little is known about the oral conditions of individuals with the forms of arthritis that affect children and adolescents, i.e. juvenile idiopathic arthritis (JIA), except for a higher caries prevalence. Information regarding periodontitis in JIA subjects is lacking and thus is needed.In conclusion, this thesis shows that adolescents with JIA, especially those more systemically affected, have a worse periodontal condition than controls. However, longitudinally, the effects of disease remission and anti-rheumatic treatment are potentially able to modulate the inflammatory process in the periodontium.

 

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Categorie: gebit - artritis

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