How ecstasy can kill brain neurons by cutting their power supply

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Omschrijving
Research by Portuguese scientists reveals how ecstasy can compromise the neurons in the brain by damaging their mitochondria – the structures responsible for energy production in the cell - causing the equivalent to a “power-cut” on the affected neurons. The work to be published in the Journal of Neuroscience[1] also reveals that a drug used in Parkinson’s disease is capable of prevent this damage. By showing how ecstasy can directly compromise such a crucial cellular process the research might help an eventual resolution of the two decade-long debate over whether or not ecstasy use is dangerous. MDMA (the main component of ecstasy) leads to the production and accumulation of serotonin, a feel-good chemical, which is behind the pleasant effects of the drug. But scientists also know that ecstasy leads to excessive, and most probably toxic quantities of serotonin accumulating in the nerve endings. How this affected ecstasy users, however, was until now not known..

 

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Categorie: ecstacy

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