Discovery of widespread tumour growth gene holds promise for effective anti-cancer treatment

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Omschrijving
Italian scientists will announce today (Monday September 24) that they have found a new and promising target for anti-tumour therapy in cancer. Professor Saverio Alberti, from the CESI, University of Chieti Foundation, Chieti, will tell the European Cancer Conference (ECCO 14) that he and his team have found a widespread mechanism for the stimulation of tumour growth in man, and that this is leading to the development of novel diagnostic and therapeutic procedures. Professor Alberti and his team have discovered the function of the Trop-2 gene, a product of the TACTD2 gene, which is expressed in placenta, an ‘invasive’ normal tissue. “The function of Trop-2 was a mystery until now,” says Professor Alberti, “but knowing its expression in the trophoblast (cells forming the outer layer of the blastocyst – the stage between the fertilised egg and the embryo) during pregnancy, we thought that it might well be involved in another invasive function – tumour growth.”

 

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Categorie: kanker

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