Microscopic Pollution May Trigger Heart Attacks/Strokes by Spurring Blood Clots

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Omschrijving
It was a murder mystery playing out in major cities across the country and perplexing scientists. Thousands of people were dying from strokes and heart attacks within 24 hours of a spike in microscopic pollution -- tiny particles that spew from the exhaust of diesel trucks, buses and coal-burning factories. But scientists didn't have a smoking gun. They couldn't figure out why the pollution was triggering the deaths. All they had to go on was a vague lead: the particles -- too small to be filtered by the nose or mouth -- caused inflammation of the lungs. But what was the link between particles trapped in the lungs to the strokes and heart attacks? New research from the gumshoes at Northwestern University's Feinberg School of Medicine has solved a key piece of the mystery. The study identifies how these tiny pieces of soot -- called particulate matter air pollution -- kill people at risk and tells how they can protect themselves from these pollution-related strokes and heart attacks. Northwestern researchers have discovered that this microscopic air pollution - smaller than 10 microns or less than one-tenth of the diameter of a human hair -- spurs hyperclotting of the blood. The study found that lungs inflamed by the pollution secrete a substance, interleukin-6, which causes an increased tendency for blood to coagulate or clot. This raises the risk of a fatal heart attack or stroke in people with cardiovascular disease such as coronary artery disease, congestive heart failure or a history of stroke.

 

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Categorie: hart

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